ALOT: Acute Leukemia Orientation Tube
he ALOT kit designed by the EuroFlow™ consortium contains a combination of 8 antibodies for initial assessment of the nature of immature populations of hematopoietic cells in samples under suspicion of acute leukemia.
This antibody combination also allows appropriate orientation towards the proper characterization panel (BCPALL, T-ALL and/or AML).
The ALOT kit allows for fast and efficient orientation in acute leukemia diagnosis.
Integrated analysis of samples stained with the ALOT screening tube is proven to be an unprecedentedly robust tool for acute leukemia diagnosis. The ALOT combination provides an orientation efficiency of 98.3% for nonambiguous lineage cases, and has been tested prospectively at different centers (van Dongen et al. Leukemia 2012; 26:1908–1975).